Destroy All Humans!

Pause the game while on the Mothership, then hold L and press Black(2), White(2), L, R, L, R, White, Black.

Complete the indicated level to unlock the corresponding movie under the B-Movie Theater option.

Every chance you get, do not kill a human before you extract their brain stem. Extract their brain stem first as it will make the DNA worth more (25 instead of 10). The easiest humans to do this to are the scientists in the level with glowing cows. For some reason, if the person that is important to you dies (the person you need to abduct), extract their brain stem before you return to the Mothership -- the DNA is usually worth more. Additionally, it is rare to find humans with brain stems that are worth 50 or 100 DNA. Most humans have brain stems that are only worth 10 or 25 DNA. If you walk around Union Town, there will be humans with signs on them reading, "REPENT THE END IS NEAR". Those humans will have a brain stem worth 50 DNA. Also, Mystery Agents' brain stems are worth 25 DNA points most of the time, whether dead or not.

When you pick something up, you can control it with the Right Analog-stick.

Pause the game, then hold L and press Black, White, Y, Right, White, Y. Your concentration meter must be above 0% or you will not be able to use any of your mental abilities.

Use your PK ability on a Majestic limo; hold L the whole time. Get a wall between you and the car, then start running away from the wall until the car smashes into it. Keep running backwards and the car will eventually explode. This trick can also be used to take out normal cars and people.

Enter a collect brain stem puzzle and find out how many brain stems you need. Then, stand around and extract the brains and leave them laying close by. When you have enough, go to the challenge and enter it; you can easily win by doing this.

While using the jetpack, quickly tap A to go farther distances.

When done with a mission at the capital city, enable the "Deep Thinker" and "Bulletproof Crypto" codes. Go to the bridge that goes to the octagon. Attack the people to get the robots to attack you. Use the mind control on the robots and lay them about over the edge. You can see a robot arm pulling the robot into the water.

While extracting a person's brain stem (alive or dead), quickly tap B. You will get their DNA easier. This is useful against the M Agents and Psi G-Men.