Nuclear Throne

Attack Big Dog with a weapon that does high damage and has good range. This includes automatic rifles, crossbows, rocket launchers, laser weapons. Avoid using short range weapons such as shotguns, grenade launchers, or disk launchers. He will use large burst attacks that will make short range combat difficult. Keep at a distance and focus fire at a decent range. Take down any rockets that are approaching you. When he dies, his final explosion can be lethal. Additionally, any cars close to him can also explode.

Enter the golden car with a "screwdriver" in level 3-1 to advance to level 3-?. Find the chest containing the golden weapon. Collect it, then complete the level.
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Skip a large radiation canister and Horror should appear in the following level. A Large radiation canister will only appear in the level after a regular radiation canister is skipped.

Find the Disc Gun then shoot it against a wall to kill yourself.

One of the red cars in level 3-1 is golden. Hit it with a "screwdriver", then enter the car.