This is done easier on a second playthrough, as you will retain your perk and weapon upgrades and know strategies to deal with various enemies and Bosses. Additionally, you do not have to complete the entire game again. Just choose the final level under the Über difficulty setting. During your playthrough make sure to use cover. Enemies will deal a lot of damage under the Uber difficulty, but the majority of them will die quickly. Keep your distance to force enemies to miss. Use stealth, especially during earlier chapters where you are at a disadvantage. You can kill the majority of enemies by sneaking up and killing them with your knife or pistol; or simply ignore enemies altogether. Try to unlock as many perks as possible as you progress, as they convey nice advantages. Rely heavily on the LKW (and Laser Marksman when obtained) in areas where you can recharge. The LKW can destroy the large robots with one or two shots after upgraded. Always aim for the head. You can kill normal soldiers with few headshots. In places, enemies will attack in groups, making grenades very useful in those situations.
Use the "Chapter Select" option to go back to earn perks and collectibles. If you choose "New Game" it will reset your totals. Select the Fergus timeline, Chapter 3, and the "Can I play, daddy?" difficulty setting. Progress through the first section and make sure you have at least one grenade. Enter the gate house and move to the left. Enter the elevator and hot-wire it to reach the top floor, which has some steel beams under the train bridge. There is a spawn point for an attack drone on the other side and a checkpoint just before it. Note: You can also find a health upgrade nearby. Take out a grenade and begin walking towards the other side. The flying attack drone will spawn below the walkway, on the right side. Throw the grenade at the walkway in front of you, where the drone appears. It should get stuck in the environment and kill the drone. Pause game play, restart the last checkpoint, and repeat the process until the Perk is earned.
The in-game description states "Kill 5 enemies in 10 seconds using a detached turret", but you do not have to use an actual turret. The Super-soldaten's chain gun also will qualify, as they are basically detached turrets.