Plague Inc: Evolved

Start with the Simian Flu under the casual difficulty setting. Genes will not matter. The ATP boost might speed things up, but is not necessary. Choose either the USA or Saudi Arabia. Progress as usual, popping DNA bubbles, until you have enough to evolve the "Simian Neuro-Genesis", which should cost 15 DNA points at the "Abilities" screen. Afterwards you will get the option to Devolve it at the cost of more DNA points.

Using Necroa Virus, combine the Vampiric Hunger symptom (Cytopathic Reanimation + Anaerobic Resuscitation + Enhanced Sensory Integration + Temporal Lobe Manipulation + Cathemeral Shift) and the Bat 1 + Bat 2 transmissions.

Play the Necroa Virus scenario and evolve your virus to have both the Hyperosmia and Delirium traits under the "Symptoms" tab.

Choose the Virus. Progress as usual and focus on mutation to get the ability to mutate Transmissions. Concentrate on resistances and transmissions first. Exit to the main menu if any of the islands such as Greenland or Madagascar close their borders or ports before they become infected, or if you have other problems such as the cure appearing too quickly. This will not count as a lost game. Note: Do not select "Retry" at the end screen, as this will disable the "Lucky Strain" cheat. When you replay from the main menu, you must also re-enable it.

Evolve the Coughing, Diarrhea, Nausea, Pneumonia and Vomiting symptoms; as well as evolving the Livestock 1 + Livestock 2 transmissions.

Start a normal non-scenario game of Prion under the casual difficulty setting. Prion can slow down the cure forcing a longer game. Start in Saudi Arabia. Then, evolve the following in order as soon as possible: Air 1 and 2, Water 1, Neural Atrophy 1, 2, and 3, Drug Resistance, and Genetic Hardening 1 and 2. Note: Devolve every mutated symptom as soon as it appears. Evolve the following symptoms: Coughing, Sneezing, Pneumonia, Cysts, Hyper Sensitivity, Abscesses, Insomnia, and Paranoia. You will have to wait at this point, devolving all mutated symptoms. Even if the symptom is non-lethal it must still be devolved. Immediately pop the cure bubbles as they appear. If the cure progress reaches 75%, immediately evolve all three Genetic Re-Shuffles. You will eventually see the message "CDC teams hunt patient zero" followed after a few months by "CDC teams close on patient zero". Evolve the following symptoms immediately: Anaemia, Haemophilia, Internal Haemorrhaging, and Hemorrhagic Shock. They should begin killing the population at a decent rate. Do not have any more lethal symptoms, as you will need time for the final pop-up to appear. After nearly half the world us killed, the message "CDC fails to identify patient zero" should appear.

Have no symptoms and your starting country at 100% infection. You must remain at no symptoms until "Peer Pressure" is earned. Consider using Bacteria and start in a small poor country, such as Zimbabwe or Kazakhstan.

Upload a scenario then earn any other achievement.

Unlock Horse Riding and Weapon Creation. This may require some time.

Using Necroa Virus, combine the Enhanced Motor Control symptom and the Engorged Quadriceps ability.