When you are traveling across the world map you sometimes come across a small green circle that has only a bridge and a person blocking your path. If you kill him instead of answering his questions, you can get 7500 experience points and his robes which is good armor until you get the powered. If you answer his questions wrong, he hits you for over 2000 damage.
Next to San Francisco is a military base which contains a mine blocked by rubble. To open this mine, go to the shack above it. Kick it open. In one of the chests you will find some dynamite. Go back down to the mine. You will see a cart. Lower down are three metal poles which you must pick up. Put it in your inventory and use it on the cart. There should now be something polished sticking out of the cart. Right Click until your pointer is an arrow then Left Click and hold it on the cart until a small pop-up message appears. Choose the bag then select the dynamite. A few seconds later the rubble will be destroyed.
Use the following trick to get the robot form Sierra Army Depot with excellent artificial intelligence. Note: You must have at least 150% at science. Get the mission from the Wright's house in New Reno. If you arrived on the base, kill all the turrets. To open the main door, go to a small house to the southwest. Try to disarm the trap on the door and get a large old cannon bullet from a chest. Go to the power generators and find a ladder. Turn the power to 50%. Go east to a large building and use the bullet on the cannon. Activate the cannon and blow up the main door. Once you are in, to your left is a desk. Search it and you will find a note. Read it to obtain a password for the computer next to the forcefield. Enter the code in the computer to disable all the forcefields on this floor. To get access to the lift, go to the room to your right and obtain an eye. Use it next to the lift to open the door. Go to the third floor. You will see a mainframe. Activate the computer console. Talk with it so that you can help it get out of here. If you see a computer to the northernmost point of this floor, do not use it yet. Go to the eastern part of the floor and search the locker. Pick up the eye to get access to the fourth floor. Proceed to the next floor. Go to the northernmost point of the floor and use the computer. Use the following options: "Retrieve", "Select Organs", and "Retrieve Brain". You will see the following brains: Abnormal Brain, Human Brain, Chimpanzee Brain, and (if your science is over 150%) Cybernetic Brain. Obtain the Cybernetic Brain, which is the best. Find a robot on any floor that looks like it has a brain and wields a rifle. Kill it. Obtain its motor. Go to the third floor and go to the room with the computer that was not used earlier. Enter the other room and you will find a robot. To the right of the robot is a Bio Med Gel. Take it. Use the Bio Med Gel, Cybernetic Brain, and Motor on the robot. Activate the computer, then select the option "Systems Check". It should say "Ready to activate" at the end of the line. Select "Begin start sequence". Talk to the robot and tell it to follow you. It is an expert at rifles, SMGs and pistols. The only bad thing about the robot is its speed, which is slow.
To learn how to skin geckos, save Smilely the trapper in the toxic caves. Then, go to Klamoth and talk to Smilely at Buckners.
Give Mayron as many ingredients for the stimpacks and antidote as needed, and he will create them.
Start a new game with a female character named Buffy. Get past the Temple Of Trials and go to the Den. Talk to Rebecca. She will say that she recognizes you and give some items.
Vic the trader is a prisoner at the slavers guild in The Den. Free him and he will join you.