Right click "Dungeons of Dredmor" in your Steam Library and select the "Properties" option. Select the "Set Launch Options" button on the "General" tab. Enter -debug-flag in the dialog box. Select "OK" to accept the change. Begin the game, then press any of the following case-sensitive keys during game play to activate the corresponding cheat function. Additionally if you click anywhere on the mini-map, you will teleport to that room.
Start a new game and progress until you find a Muscle Diggle. Kill all enemies around it, or bring it away from other threats. Stand next to the Muscle Diggle and advance your turn until it kills you.
Craft The Bomb by gathering a Aetheric Power Cylinder, Bolt of Mass Destruction, Vodka, Orb of Nothing, and n-Dimensional Lathe. You also must have Wand Crafting at level 7. All the components except the Orb of Nothing are craftable or can be purchased from vending machines. The Orb of Nothing is a nine-star item and can be obtained in very deep levels of the dungeon. Having the Realm of the Diggle Gods DLC is recommended to extend the dungeon from 10 to 15 floors to increase the odds of one dropping there or appearing in one of Brax's shops. After The Bomb is crafted, save it until you find a Monster Zoo. Save the game, then throw it in the zoo. If the achievement is not earned the first time, reload the saved game and repeat the process.
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Contrary to the description, you will need all three primary damage types and thirteen special damage types. This will require careful planning and item collection. Weapons will usually have one or two of the primary damage types, but on rare occasions can possess all three (Crushing, Slashing, Piercing). Dual-wielding two different types may help. Any piece of equipment can possess at least one special damage type. Artifacts from quests and evil chests on average have more. With luck, you can add special damage types through the use of Krong Anvils. Having the Archaeology skill tree This Translation Is All Wrong (randomly changes damage types on items) and Ancient Kronian Ritual (lets you use a Krong Anvil twice) may help. You can also gain specific special damage types temporarily with the use of potions and mushrooms. The special damage types required are as follows.
The Conquest of the Wizardlands DLC is required to enter Diggle Hell. Once in your Pocket Dimension, enter an invalid code into the Portal. The Portal will turn red instead of black, indicating that it now leads to Diggle Hell and not to a Wizardland. Each Diggle Hell level is randomly created (even if you enter the same invalid code as used in a prior visit), and randomly includes a statue of the Diggle God of Hell. Several visits to Diggle Hell may be required to find a "Statue of the Diggle Devil". A high level character is recommended in order to survive. Once a statue is found, click it and answer "Yes" to receive a powerful permanent fire-based buff (until you are blessed by another Diggle God) and earn the achievement.
Try using a build that is based on the Mage Archetype or crossbows/thrown weapons. You can try defeating Lord Dredmor on either level 10 or 15. Take a large amount of lockpicks to the last level. Kicking a door will destroy it, and you will then not be able to open and close it to your advantage. Once you find him, close the door, drink all Elemental potions, the Potion of Steeling, Radiance and Dire Empowerment (all of which except Steeling will stack up to three times). Fungi will also help, mostly Plumber's Agaric, Prince, Fell Truffle, Grunge Ear and Lobstermane. If you need to restore health, use an Inky Hoglantern or Potion of Invisibility. If desired, you can also use a Spatial Instability potion or any teleport while invisible to escape his melee attacks. Then, restore your health by eating Fairy Wodgers, drinking Lively Regeneration, Healing or Replenishment potions or using a Coral wand. You can remove his debuffs with Zodiacal wands and Potions of Purity. Firing crossbows will take advantage of Lord Dredmor's weakness to piercing damage. He is also susceptible to Righteous damage. Firing Bolts of Doubt, Clockwork Drill Bombs, Clockwork Drill Bolts and Fire Bolts can decrease his health steadily. Thrown weapons such as the Holy Grenade and Clockwork Sawblade are useful, but not as effective as crossbows. If possible, obtain the "Golden Crossbow", which is an artifact crossbow which sometimes appears in shops. Despite its very low damage and -5 EDR, a successful hit with it will debuff your target with "Inevitable Doom", which kills it after 100 turns. However this will result in a one hit kill when used against Lord Dredmor due to the length of the encounter.
Note: This requires the Conquest Of The Wizardlands DLC. Vlad Digula can be found in Diggle Hell, which is entered by entering a wrong Arcane address at the gate inside a Pocket Dimension. Once inside, you cannot exit until you find the gate back, and the enemies are difficult. Vlad Digula has high stats and can kill you quickly with his spells. Get his attention, then close a door between you and him. He will remain at the door, allowing you to still use some spells to hit him. Vlad is vulnerable against Righteous, Acidic, Putrefying and Aethereal damage. Consider using Egyptian Magic to damage him. Activate the first three glyphs to increase the damage radius of Call the Storm and use Glyph of Anubis to do Putrefying damage.