Mass Effect

Start a New Game, then select to use existing Career. You'll be playing with your older character (with all items and skills intact).

If you beat the game and choose to replay the game with the same character, your character type will be able to learn some skills he or she would otherwise be unable to learn. For instance, on a second play-through, Adepts can learn to use Shotguns, First Aid, and other skills they were otherwise unable to use the first time through.

On the planet Noveria you must solve a puzzle after you enter the Core at Mira to restore activity to the compound. The solution is as follows. There are three columns. Four discs are in the left column. You must move all four discs to column two or three for the puzzle to be completed. "1" indicates the upper most ring, "4" is the lowest, etc.

Step 1
Move 1 to the middle.
Move 2 to the right.
Move 1 to the right on top of 2.
Move 3 to the middle.

Step 2
Move 1 to the left.
Move 2 to the middle on top of 3.
Move 1 to the middle on top of 2.
Move 4 to the right.

Step 3
Move 1 to the right.
Move 2 to the left.
Move 1 to the left on top of 2.
Move 3 to the right on top of 4.

Step 4
Move 1 to the middle.
Move 2 to the right.
Move 1 to the right.

These steps will solve the puzzle with all four discs being in the right column.

After beating Mass Effect, you can play through the game again, with the same character, same skills, items, etc.

Play as a War Hero Soldier first. By doing this, during your second play through you will have all of the money, weapons, and armor to use for the other careers.

When you have landed on Luna, Earth's moon, look for the view of Earth. When you zoom in on Earth, noticed that its image is reversed. For example, Florida is where California should be and vice versa.

Gain the Distinguished Combat Medal achievement.

Sentinels combine biotic and tech abilities. Typically they use biotic abilities and advanced healing skills to defend allies, though they can also disrupt opponents with biotic or Tech attacks. They are more efficient at tech and biotics than other classes, but at the expense of combat. Sentinels can only use light armor, and receive no advanced weapon training.

When looking for certain items or armor, save before talking to merchant for first time. The merchandise is random. If you do not get anything you want, reload the game and talk to the merchant again. This trick can be used about three times whenever enough game time has elapsed for merchants to respawn new items.

Soldiers are combat specialists ideal for the front lines of a firefight. Soldiers begin the game trained with skills in both pistols and assault rifles, they have improved health and the ability to wear medium combat armor. As you progress through the game you can unlock assault training, skills with shotguns and sniper rifles, become able to perform first aid on yourself and party members, and wear heavy combat armor.