BioShock

To defeat Frank Fontaine very fast, when you first enter the room hit him with the tool the Little Sisters gave you. Fight him when he throws you off. Once he is back on the bed, run up and hit him again with the tool to drain his Adam. This works a lot faster due to him only have four or five jars of Adam to drain, and the fights are not very long afterwards.

When the dark cloud envelopes the icy battlefield upon which you must face Peach Wilkins, save the game and locate the hostile turret at the end of the room when the cloud clears. Load the game and run to it before the cloud clears, so that you can quickly freeze or shock it. Then, hack it so it shoots your enemies. Crouch down by the area to your right when facing the turret. There are a few barriers here to protect you from enemy fire. However, to avoid damage by Wilkins' grenades, keep Telekinesis as your active Plasmid. He will avoid the turret's fire, but as long as you stay behind the barriers by the turret he will stay at a safe distance. This gives you time to calmly return his grenades using Telekinesis until he dies. The turret will take out most of the Splicers. This method makes things much easier because it eliminates the hectic "run around and whack people with the wrench" strategy that is otherwise your only option. That turret if not used as an ally would probably be the main cause of your death, along with the bots triggered by the security camera. By hiding near the allied turret however, you also hide from the camera's view.

When fighting a Rosie, use armor piercing rounds from the machine gun or pistol. For a more effective way of killing, launch frag grenades and run out a door. The Rosie will follow you, fire proximity mines at the door, and when it walks through it will be damaged or destroyed.

While in levels that have more than one Little Sister in them, you may see a Rosie roaming the level alone. The following should only happen if you have already harvested or saved at least one, but not all the Little Sisters in that level. The lone Rosie will walk up to one of the many holes in the walls through which the girls crawl through. It will bang on the metal and wait. Then it will help a Little Sister jump down from the opening. The girl will then lead the Rosie throughout the level. Therefore, when hunting these formidable enemies, do not attack or ignore a Rosie if it walks alone (as long as in the pause screen it says that there is still at least one Little Sister remaining). Rather, follow it. Wait for it to summon a Little Sister out of the wall, then attack it using whatever strategy suits you. If you attack it when it's alone you will not get to harvest or save any Little Sister as a reward for killing it.

If you are up against a stationary security robot (RPG, etc.), use Telekenesis to grab a crate or pallet. Hold it in front of you until you can find a place to hide and plan what to do next. The item you hold up will block some attacks.

  Xbox 360   Reach the end of the game under the Easy or Normal difficulty. Get Atlas down to his last jar of Adam. Pause game play, go to the "Options" menu and change the difficulty to "Hard". Defeat Atlas to unlock the achievements or trophies. Note: You cannot die while unlocking the "Brass Balls" achievement or trophy.

Do not harvest a single Little Sister throughout the game. Tenebaum will reward you with gifts (including Adam) every time you rescue three Little Sisters. This proves more effective, as you get the same amount of Adam as you would if you harvested them but you also get the achievement.

When buying Plasmids, Tonics, and Upgrades from the Gatherer's Garden, always buy the Tonics first. Then, make sure you search every area for other Tonics. When you reach Point Prometheus there will be three Tonics to find. The rest of the Tonics are available in the Gatherer's Garden. This will ensure you get the achievements. Note: To check how many Tonics you have, go to a Gene Bank and count each "track".

From the start you will have a wrench and the Electric Bolt Plasmid at your disposal. Using these is rapid succession against most Splicers can often result in an efficient, quick kill. First, shock the Splicer. Before the convulsion ends, switch out the wrench, aim high, and hit the Splicer over the head. The most efficient way of eliminating the agile Spider Splicers however is to unleash a few clips of anti-personnel ammo, preferably from the machine gun.

When you find any slot machine, use Incinerate Plasmid to corrupt the machine. You will nearly always win money when you use the burnt out machine.

Just after receiving The ADOM extractor from the Little Sister, do not take the elevator to the last fight. Instead, go through the rooms you missed along the way. Cameras , turrets, Splicers, and Big Daddies will not see you, and electric trap bolts will not hurt you.